Saturday, 9th February 24th Annual Lorne Proteomics Symposium 2019

• Components of reproducible quantitative mass spectrometry-based research: a statistician's perspective - Olga Vitek
• Toffee: A highly compressed file format for time of flight and orbitrap DIA-MS - Brett Tully
• LFQ-Analyst: An interactive web-platform to analyse quantitative proteomics data - Anup D. Shah
• Signalling networks in the analysis of proteomic data - Hannah Huckstep

• An atlas of protein-protein interactions across mammalian tissues - Leonard Foster
• Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy - Albert Lee
• Systems proteomics of the intermittent fasting response highlights the importance of HNF4A - Mark Larance
• Systems immunology reveals the importance of direct and cross-presentation in driving cytotoxic T lymphocyte responses to distinct epitopes - Nathan P Croft
• Integrated time-series analysis of proteomic and transcriptomic profiles for activated human T-cell function - Ahmed Mohamed
• New insights into HLA-B27 peptide repertoire: Elucidating the connection between Salmonella infection and ankylosing spondylitis - Terry C.C Lim Kam Sian

• Peptides and Penicillins: Identifying the immunogenic β-lactam ligand(s) - Shawn Goh
• Using genomics and proteomics to understand the antibiotic resistance capabilities of an isolate - Stephanie E L Town
• Extractomes profiling reveals potential role of key proteins in Staphylococcus aureus biofilm using TMT-based quantitative mass spectrometry - Md Arifur Rahman
• Accessing the mannose-6-phosphate glycoproteome using titanium dioxide (TiO₂) enrichment - Sayantani Chatterjee
• The role of upstream phosphorylation in the regulation of histone methylation - Ryan J Separovich
• Characterisation of human adipose stem cells - Naomi Koh Belic 

• Peptides and Penicillins: Identifying the immunogenic β-lactam ligand(s) - Shawn Goh
• Using genomics and proteomics to understand the antibiotic resistance capabilities of an isolate - Stephanie E L Town
• Extractomes profiling reveals potential role of key proteins in Staphylococcus aureus biofilm using TMT-based quantitative mass spectrometry - Md Arifur Rahman
• Accessing the mannose-6-phosphate glycoproteome using titanium dioxide (TiO₂) enrichment - Sayantani Chatterjee
• The role of upstream phosphorylation in the regulation of histone methylation - Ryan J Separovich
• Characterisation of human adipose stem cells - Naomi Koh Belic
• EasyPep - A new simplified and optimized workflow for MS sample preparation - Michael MM Mariani
• Dietary selenium significantly effects rat liver protein expression - Larissa Lago
• Development of an immune response assay for honey bees   - Shannon Holt
• Potential protein biomarkers for the diagnosis of early stage gastric cancer - Chris Desire
• A mass spectrometry quality control website: monitoring SCIEX instruments to maximise productivity - Katherine E Scull
• Desorption electrospray ionization and data independent analysis profiling of the lipid complement of lysosomal storage disorders  - David Heywood
• Optimised Desorption Electrospray Ionisation Mass Spectrometry Imaging (DESI-MSI) method for the analysis of proteins/peptides directly from tissue sections - David Heywood
• Top-down, middle-down and bottom-up proteomics analysis of medicinal cannabis - Delphine Vincent
• Identifying PTM changes from DIA data – a computational workflow - Jemma Wu
• From raw data to biological insights: A computational pipeline for SWATH-MS-based proteomics - Srikanth S. Manda
• Transpeptidation is a major mechanism of haemoglobin proteolysis by the gingipain cysteine proteinases - Paul D Veith
• Using quantitative proteomics to resolve genomic diagnosis of mitochondrial disease - Daniella H Hock
• An integrated -omics approach to overtraining biomarker discovery - Jessica van Haeften
• Defining the contribution of linear and spliced peptides to the anti-influenza T cell response - Patricia Illing
• Development of an optimized end to end phosphoproteomic workflow on the timsTOF PRO - Rune H Larsen
• Development of proteomic tools to identify telomere maintenance mechanisms in human cancer - Yangxiu Wu
• Recognising the role of post-translational modification in immunopeptidomic peptides by using mass spectrometry and bioinformatics - Shutao Mei
• Proteomics unravel novel molecular mechanisms of Alzheimer’s disease in retina              - Mehdi Mirzaei
• Analysis of cysteine redox post-translational modifications in a rat model of type II diabetes mellitus   - Shivanjali J Lingam
• Detection of collagen proteins of bovine and porcine origin in food products using targeted LC-MS - Matthew J Fitzhenry
• Understanding the roles of subunits and assembly factors implicated in the biogenesis of human Complex II - Joanna Sacharz
• Improved lipid annotation utilizing positive and negative ion MS² / MS³ HCD and CID spectra  - Amanda Souza
• A multiplexed enrichment and targeted PRM platform for absolute quantitation of AKT/mTOR, Ras, and p53 signaling pathways targets - Steve Binos
• Degradomic analysis of a putative C-terminal processing peptidase  from Campylobacter jejuni - Joel A Cain
• Detect more proteins with decreased false positives using filtered SWATH peptide libraries to improve plasma biomarker studies - Mark P Molloy
• Exploring the bacteriophage φX174 infection response - Bradley W Wright
• Proteomic profiling of the cell surface of senescent cells  - Birgit Schilling
• The role and regulation of Atg1 in autophagy and DIF-1 induced autophagic cell death of Dictyostelium discoideum - Melodi G Sen
• Using integrative multi-omics to explore Pseudomonas aeruginosa cellular physiology after adaptation to the Cystic Fibrosis lung - William Klare
• Development of a quantitative proteomic standard for Tandem Mass Tags (TMT) - Samah Issa
• AI-based solutions for MS-based immunopeptidomics with high sensitivity and accuracy - Paul Shan
• MS evidence acquisition of missing proteins in chromosome 9 using halo tag purification system and identification of cellular roles. - HuiSu Kim

Thermo Fisher Scientific Annual Users Meeting

See how our mass spectrometry solutions for HRAM Orbitrap™ systems coupled with powerful software can help you be selective and rise above the noise. From leading edge biological research to translational medicine, hear from renowned guest speakers. 
For our annual Lorne user meeting workshop, the aim is to present technology, with workflows that improve throughput to simplify and answer complex biological questions. Our guest speakers are three eminent researchers in their field within ANZ. 
Dr Ralph Schittenhelm from Monash University will be presenting a DIA phosphoproteomic study in response to inflammation and Dr Nicholas Scott from The University of Melbourne will present on protein-protein interactions across mouse tissues. 
Closing the session will be an update on the newly released FAIMS Pro in routine plasma analysis.

Topics/ key words:
Proteomics, DIA, DDA, FAIMS, Ion Mobility, clinical trial, HF-X, plasma, Fusion Lumos, Host Pathogens Interactions , Immunology, Emerging Infections

Speakers:

• Mark Larance, Ph.D. (CINSW Future Research Leader Fellow, The CPC, Sydney)
  "Bloody Plasma Proteomics"

• Steve Binos, Ph. D (Thermo Fisher Scientific, Melbourne, Scoresby)
  "Plasma Proteome Profiling Using the FAIMS Pro Interface on the Fusion Lumos Tribrid Mass Spectrometer"

• Prof Leonard Foster (Michael Smith Laboratories, UCB, Canada)
  “Maximizing proteoform coverage with the timsTOF Pro and Julienne”
  
  
• Prof Ron Heeren(M4I, Maastricht University, The Netherland)
  “Translational imaging mass spectrometry: Combined throughput and resolution”
  
  
• Mr Rune Larsen 
  "Realising the potential of ultrasensitive Phosphoproteomics on the timsTOF Pro"

• Glycosylation in sparkling wines - Benjamin L Schulz
• Proteomics reveals multiple phenotypes associated with N-linked glycosylation in Campylobacter jejuni - Joel A Cain
• Post-Column Make-up Flow (PCMF) of organic modifiers enhances the sensitivity of capillary-flow PGC-LC-MS/MS-based glycomics - Hannes Hinneburg
• Dynamic cellular glycoproteome and proteome during influenza infection - Cassandra L Pegg

• Application of ion mobility and electron capture dissociation (ECD) mass spectrometry to top-down and bottom-up proteoform characterization - Blaine R Roberts
• Laser ablation for tissue sampling for proteomics and metabolomics - Hartmut Schlüter
• Evaluation of a novel LC system that embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics - Nicolai Bache
• Reversed phase x reversed phase on-line comprehensive two-dimensional liquid chromatography of intact proteins with triple quadrupole mass spectrometric detection - Kevin Schug